Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13090360 | 0.93 | CYP2C19 (0.78) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL16405166 | 0.89 | CYP2C19 (0.55) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL13609095 | 0.87 | GABRA1 (0.52) | CYP2C19ALOX15MAPK1HTTCYP2D6 | |
| SCHEMBL16477789 | 0.86 | CYP2C19 (0.64) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL13994537 | 0.81 | CYP2C19 (0.62) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL6057620 | 0.81 | ALOX15 (1.00) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL7117673 | 0.81 | CYP2C19 (1.00) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL16168753 | 0.81 | CYP2C19 (0.46) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL13090362 | 0.78 | POLB (0.53) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL11828033 | 0.77 | CYP2C19 (0.66) | CYP2C19ALOX15MAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015068156-A1 | COMPOUNDS FOR THE TREATMENT OF DIABETES AND DISEASE COMPLICATIONS ARISING FROM SAME | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2015-05-14 | — | — | WO | disclosed |