Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712705 | 0.89 | CYP2C19 (0.68) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL16477789 | 0.86 | CYP2C19 (0.64) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL13090360 | 0.83 | CYP2C19 (0.78) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL13609095 | 0.78 | GABRA1 (0.52) | CYP2C19ALOX15MAPK1HTTCYP2D6 | |
| SCHEMBL4583688 | 0.75 | ALOX15 (0.55) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL199679 | 0.74 | CYP2C19 (0.53) | CYP2C19ALOX15MAPK1HTTCYP2D6 | |
| SCHEMBL959023 | 0.74 | ALOX15 (0.53) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL11822725 | 0.74 | CYP2C19 (0.58) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL12285794 | 0.73 | ALOX15 (0.43) | CYP2C19ALOX15MAPK1HTTALDH1A1 | |
| SCHEMBL3654451 | 0.73 | ALOX15 (0.52) | CYP2C19ALOX15MAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826472-A2 | Telomerase activating compounds and their use | Ben Gurion University Of The Negev Research And Development Authority (IL) | 2015-01-21 | — | — | EP | disclosed |