SCHEMBL16712976

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18085949	0.90	SMN1; SMN2 (0.57)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL10983794	0.86	P2RX7 (0.64)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL7029110	0.86	PRKD3 (0.57)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL29770053	0.84	ROCK2 (0.77)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL2910551	0.83	ROCK2 (0.64)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL2905832	0.81	ROCK2 (0.61)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL18085946	0.80	ROCK2 (0.55)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL10988523	0.80	ROCK2 (0.79)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL2909149	0.80	ROCK2 (0.59)	ROCK2ROCK1CCR2PRKD3PRKCG
	SCHEMBL14818897	0.80	ROCK2 (0.67)	ROCK2ROCK1CCR2PRKD3PRKCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.