Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 3/20 | 0.57 |
| ▸ | PRKCG | P05129 | 3/20 | 0.57 |
| ▸ | PRKCB | P05771 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | PRKCA | P17252 | 3/20 | 0.57 |
| ▸ | PRKCH | P24723 | 3/20 | 0.57 |
| ▸ | PRKCI | P41743 | 3/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.57 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | PRKACA | P17612 | 2/20 | 0.57 |
| ▸ | PRKACG | P22612 | 2/20 | 0.57 |
| ▸ | PRKACB | P22694 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 13/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10987738 | 0.90 | P2RX7 (0.65) | PRKD3PRKCGPRKCBCYP3A4PRKCA | |
| SCHEMBL7029577 | 0.87 | GPR183 (0.54) | HTR1AMEN1KMT2AKCNH2SMN1; SMN2 | |
| SCHEMBL16712976 | 0.86 | ROCK2 (0.57) | PRKD3PRKCGPRKCBCYP3A4PRKCA | |
| SCHEMBL10980155 | 0.82 | PRKD3 (0.65) | PRKD3PRKCGPRKCBCYP3A4PRKCA | |
| SCHEMBL7027668 | 0.81 | FABP1 (0.65) | HTR2A | |
| SCHEMBL10983918 | 0.80 | PRKD3 (0.67) | PRKD3PRKCGPRKCBCYP3A4PRKCA | |
| SCHEMBL10983794 | 0.79 | P2RX7 (0.64) | PRKD3PRKCGPRKCBCYP3A4PRKCA | |
| SCHEMBL7028323 | 0.79 | POLB (0.50) | CYP3A4CYP1A2HTR1ACYP2D6MEN1 | |
| SCHEMBL2905832 | 0.79 | ROCK2 (0.61) | PRKD3PRKCGPRKCBCYP3A4PRKCA | |
| SCHEMBL29120406 | 0.79 | PRKD3 (0.60) | PRKD3PRKCGPRKCBCYP3A4PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130287-A1 | Piperidine and piperazine derivatives which function as 5-ht2a receptor antagonists | MERCK PATENT GMBH (DE) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130287-A1 | Piperidine and piperazine derivatives which function as 5-ht2a receptor antagonists | HTR2A, HTR1A, HTR5A | PRKD3 2270/4885PRKCG 2893/4885PRKCB 2840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.