Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.42 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL16713047 | 1.00 | EPHX1 (0.44) | EPHX1GPR84PPARGPPARDPPARA | |
| SCHEMBL22000806 | 0.82 | — | — | |
| Octane SCHEMBL28966088 | 0.79 | GPR84 (0.62) | GPR84PPARGPPARDPPARAHDAC11 | |
| Glycine SCHEMBL27460334 | 0.77 | TSHR (0.52) | EPHX1GPR84PPARGPPARDPPARA | |
| Glycine SCHEMBL28934964 | 0.76 | S1PR2 (0.58) | EPHX1TSHRALDH1A1 | |
| SCHEMBL28111131 | 0.76 | EPHX1 (0.50) | EPHX1 | |
| Spermine SCHEMBL27579248 | 0.76 | PAOX (0.56) | TSHRALDH1A1MEN1ALOX15KMT2A | |
| Spermine SCHEMBL1740431 | 0.76 | PAOX (0.56) | TSHRALDH1A1MEN1ALOX15KMT2A | |
| Glycine SCHEMBL27452821 | 0.76 | TSHR (0.50) | EPHX1GPR84PPARGPPARDPPARA | |
| SCHEMBL6183701 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828572-B2 | Method for removing odor of artificial leather and artificial leather manufactured using the same | Hyundai Motor Company Kolonglotech, Inc. (KR) | 2017-11-28 | — | — | US | claimed |
| US-20150140311-A1 | METHOD FOR REMOVING ODOR OF ARTIFICIAL LEATHER AND ARTIFICIAL LEATHER MANUFACTURED USING THE SAME | KOLONGLOTECH. INC. (KR) | 2015-05-21 | — | — | US | claimed |
| US-9828572-B2 | Method for removing odor of artificial leather and artificial leather manufactured using the same | Hyundai Motor Company Kolonglotech, Inc. (KR) | 2017-11-28 | — | — | US | disclosed |
| US-20150140311-A1 | METHOD FOR REMOVING ODOR OF ARTIFICIAL LEATHER AND ARTIFICIAL LEATHER MANUFACTURED USING THE SAME | KOLONGLOTECH. INC. (KR) | 2015-05-21 | — | — | US | disclosed |