Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | APEX1 | P27695 | 1/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15354269 | 0.86 | ALDH1A1 (1.00) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL16713290 | 0.83 | KMT2A (0.66) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL19367867 | 0.80 | ERCC5 (0.54) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL29029980 | 0.79 | KMT2A (0.85) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL16713276 | 0.78 | KMT2A (0.75) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL30977784 | 0.78 | KMT2A (0.75) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL181841 | 0.77 | ALDH1A1 (0.74) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL3953437 | 0.76 | ALDH1A1 (0.73) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL29377294 | 0.75 | KMT2A (0.70) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL8437671 | 0.73 | ALDH1A1 (0.68) | KMT2AALDH1A1MEN1POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071550-B1 | METHOD OF PREPARING FUSED RING INDENO COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2019-03-13 | — | — | EP | disclosed |
| US-9630902-B2 | Method of preparing fused ring indeno compounds | TRANSITIONS OPTICAL, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| EP-3071550-A1 | METHOD OF PREPARING FUSED RING INDENO COMPOUNDS | Transitions Optical, Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| US-20160060205-A1 | Method Of Preparing Fused Ring Indeno Compounds | TRANSITIONS OPTICAL, INC. | 2016-03-03 | — | — | US | disclosed |
| US-9206151-B2 | Method of preparing fused ring indeno compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-12-08 | — | — | US | disclosed |
| WO-2015077147-A1 | METHOD OF PREPARING FUSED RING INDENO COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| US-20150141662-A1 | Method Of Preparing Fused Ring Indeno Compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141662-A1 | Method Of Preparing Fused Ring Indeno Compounds | INHA, INTS9, CA9 | KMT2A 1445/4885ALDH1A1 198/4885MEN1 657/4885 |
| US-20160060205-A1 | Method Of Preparing Fused Ring Indeno Compounds | INHA, INTS9, CA9 | KMT2A 1445/4885ALDH1A1 198/4885MEN1 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.