SCHEMBL181841

SCHEMBL181841

O=C(c1ccco1)c1ccco1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.74
POLB P06746 3/20 0.74
KMT2A Q03164 3/20 0.74
TDP1 Q9NUW8 3/20 0.74
MEN1 O00255 2/20 0.74
RECQL P46063 2/20 0.74
THRB P10828 1/20 0.74
APEX1 P27695 1/20 0.74
CES2 O00748 1/20 0.71
CES1 P23141 1/20 0.71
PTPN1 P18031 2/20 0.62
AGTR1 P30556 1/20 0.54
MAPT P10636 2/20 0.52
ERCC5 P28715 1/20 0.52
FEN1 P39748 1/20 0.52
RAB9A P51151 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
HSD17B10 Q99714 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19458027 0.91 POLB (0.63) ALDH1A1POLBKMT2ATDP1MEN1
SCHEMBL15354269 0.85 ALDH1A1 (1.00) ALDH1A1POLBKMT2ATDP1MEN1
SCHEMBL3953437 0.84 ALDH1A1 (0.73) ALDH1A1POLBKMT2ATDP1MEN1
SCHEMBL2155972 0.83 CES2 (1.00) ALDH1A1POLBKMT2ATDP1MEN1
SCHEMBL15233 0.83 CES2 (1.00) ALDH1A1POLBKMT2ATDP1MEN1
SCHEMBL25320183 0.82 POLB (0.53) ALDH1A1POLBKMT2ATDP1MEN1
SCHEMBL11311905 0.82 KMT2A (0.60) ALDH1A1POLBKMT2ATDP1MEN1
SCHEMBL4031476 0.81
SCHEMBL8199604 0.81 CES2 (0.95) ALDH1A1POLBKMT2ATDP1MEN1
Ammonia Solution, Strong SCHEMBL11456969 0.81 CES2 (0.95) ALDH1A1POLBKMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120073226-A Separator, battery cell, battery and electricity utilization device 宁德时代新能源科技股份有限公司 2025-05-30 CN claimed
CN-108289820-B Method for cosmetic treatment of keratin materials 莱雅公司 2021-07-13 CN claimed
US-10646428-B2 Process for cosmetic treatment of keratin materials L'OREAL (FR) 2020-05-12 US claimed
CN-109310604-A Use of specific compounds for modifying, reducing or eliminating off-flavours 西姆莱斯有限公司 2019-02-05 CN claimed
US-20180344617-A1 PROCESS FOR COSMETIC TREATMENT OF KERATIN MATERIALS L'OREAL (FR) 2018-12-06 US claimed
EP-3383360-A1 PROCESS FOR COSMETIC TREATMENT OF KERATIN MATERIALS L'Oréal (FR) 2018-10-10 EP claimed
WO-2017093183-A1 PROCESS FOR COSMETIC TREATMENT OF KERATIN MATERIALS L'OREAL (FR) 2017-06-08 WO claimed
CN-106800493-A Method for reducing aromatic nitro group into aromatic amine 三峡大学 2017-06-06 CN claimed
CN-101109074-B Method to reduce gas-phase reactions in a pecvd process with silicon and organic precursors to deposit defect-free initial layers APPLIED MATERIALS INC 2010-12-15 CN claimed
EP-1740576-B1 NOVEL PIPERIDINE SUBSTITUTED DIAMINOTHIAZOLES HOFFMANN LA ROCHE (CH) 2009-07-01 EP claimed
CN-101109074-A Method to reduce gas-phase reactions in a pecvd process with silicon and organic precursors to deposit defect-free initial layers APPLIED MATERIALS INC (US) 2008-01-23 CN claimed
US-7129364-B2 Process for the preparation of 2-furyl-n-pentylketone and longer chain analogs THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2006-10-31 US claimed
US-20060094888-A1 Process for the preparation of 2-furyl-n-pentylketone and longer chain analogs THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2006-05-04 US claimed
CN-1688579-A Condensed pyridines and pyrimidines with TIE2 (TEK) activity ASTRAZENECA AB (SE) 2005-10-26 CN claimed
EP-1358169-A2 DIAMINOTHIAZOLES AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASE F. HOFFMANN-LA ROCHE AG (CH) 2003-11-05 EP claimed
WO-2002057261-A2 DIAMINOTHIAZOLES AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASE F. HOFFMANN-LA ROCHE AG (CH) 2002-07-25 WO claimed
EP-0094726-B1 PROCESS FOR THE TRANSFORMATION OF AN ALDEHYDE OR A KETONE INTO THE CORRESPONDING EPOXIDE, IN PARTICULAR OF FURFURAL INTO FURFURYL OXIRANES AGRIFURANE S.A. (FR) 1986-01-15 EP claimed
US-4014853-A REACTION PRODUCT OF OXALYL DIHYDRAZIDE AND FURFURAL, METAL DEACTIVATORS, POLYETHYLENE BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1977-03-29 US claimed
JP-63101475-A None JP disclosed
US-4014853-A REACTION PRODUCT OF OXALYL DIHYDRAZIDE AND FURFURAL, METAL DEACTIVATORS, POLYETHYLENE BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10646428-B2 Process for cosmetic treatment of keratin materials KRT18, ACR, MMAB ALDH1A1 435/4885POLB 785/4885KMT2A 355/4885
US-20060094888-A1 Process for the preparation of 2-furyl-n-pentylketone and longer chain analogs TKT, MPST, KHK ALDH1A1 730/4885POLB 1093/4885KMT2A 1875/4885
US-20180344617-A1 PROCESS FOR COSMETIC TREATMENT OF KERATIN MATERIALS KRT18, ACR, MMAB ALDH1A1 435/4885POLB 785/4885KMT2A 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.