Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4711987 | 0.76 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1MEN1KMT2AELANE | |
| SCHEMBL10720721 | 0.75 | LMNA (0.37) | L3MBTL1ALDH1A1MEN1KMT2ASLC9A1 | |
| SCHEMBL5369114 | 0.73 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9466815 | 0.68 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16713403 | 0.68 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12549725 | 0.64 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10816228 | 0.64 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31219281 | 0.64 | MEN1 (0.34) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5693982 | 0.63 | NPEPPS (0.42) | ALDH1A1MEN1KMT2AGABRA1GABRB2 | |
| SCHEMBL11319011 | 0.62 | TP53 (0.46) | L3MBTL1KDM4EPKMTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150141387-A1 | PHARMACEUTICAL PRODUCT COMPRISING A P38 KINASE INHIBITOR AND A SECOND ACTIVE INGREDIENT | ASTRAZENECA UK LIMITED (GB) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141387-A1 | PHARMACEUTICAL PRODUCT COMPRISING A P38 KINASE INHIBITOR AND A SECOND ACTIVE INGREDIENT | NR3C2, GRK4, PTGER2 | L3MBTL1 4752/4885ALDH1A1 1934/4885MEN1 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.