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SCHEMBL167138

SCHEMBL167138

CNC(=O)/C(=N/OC)c1ccccc1/C=N/OC(C)c1cccc(C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 1/20 0.36
▸ KLRK1 P26718 2/20 0.35
▸ MICA Q29983 2/20 0.35
▸ RAET1L Q5VY80 2/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.34
▸ KMT2A Q03164 4/20 0.34
▸ HTT P42858 3/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ POLB P06746 3/20 0.34
▸ LMNA P02545 2/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ PTBP1 P26599 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ ADAMTS4 O75173 1/20 0.34
▸ MMP13 P45452 1/20 0.34
▸ RXFP1 Q9HBX9 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155385 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL29645219 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL30416049 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL29459626 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL483329 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL8462213 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL154409 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL29716485 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL8461974 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL14845758 0.90 CYP1A2 (0.36) HIF1AKLRK1MICARAET1LNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 — — CN claimed
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 — — EP claimed
EP-3490379-A1 ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS Bayer CropScience Aktiengesellschaft (DE) 2019-06-05 — — EP claimed
EP-3395171-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2018-10-31 — — EP claimed
EP-3010889-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-10-03 — — EP claimed
EP-2793578-B1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-06-06 — — EP claimed
US-20180103640-A1 PROCESS FOR IMPROVING SEEDLING GROWTH AND/OR EARLY EMERGENCE OF CROPS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-04-19 — — US claimed
WO-2018019676-A1 ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-02-01 — — WO claimed
US-20170265470-A1 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-09-21 — — US claimed
US-9642363-B2 N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2017-05-09 — — US claimed
US-20030158151-A1 Fungicidal active ingredients combinations BAYER AKTIENGESELLSCHAFT (DE) 2003-08-21 — — US claimed
EP-1239733-B1 FUNGICIDAL COMBINATIONS OF ACTIVE SUBSTANCES BAYER CROPSCIENCE AG (DE) 2003-07-02 — — EP claimed
US-20030105146-A1 Fungicidal combinations of active substances BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 — — US claimed
JP-2003516979-A — — 2003-05-20 — — JP claimed
EP-1289366-A1 FUNGICIDAL COMBINATIONS OF ACTIVE AGENTS Bayer Aktiengesellschaft (DE) 2003-03-12 — — EP claimed
EP-1276375-A2 FUNGICIDAL ACTIVE INGREDIENT COMBINATIONS Bayer Aktiengesellschaft (DE) 2003-01-22 — — EP claimed
EP-1239733-A2 FUNGICIDAL COMBINATIONS OF ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2002-09-18 — — EP claimed
WO-2001084931-A1 FUNGICIDAL COMBINATIONS OF ACTIVE AGENTS BAYER CROPSCIENCE AG (DE) 2001-11-15 — — WO claimed
WO-2001080641-A2 FUNGICIDAL ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2001-11-01 — — WO claimed
WO-2001044215-A2 FUNGICIDAL COMBINATIONS OF ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2001-06-21 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105146-A1 Fungicidal combinations of active substances CYP1B1, CYP4X1, CYP1A1 HIF1A 4293/4885KLRK1 4277/4885MICA 3724/4885
US-20180103640-A1 PROCESS FOR IMPROVING SEEDLING GROWTH AND/OR EARLY EMERGENCE OF CROPS EEF1A1, BTF3, EEF1A2 HIF1A 1481/4885KLRK1 4818/4885MICA 4587/4885
US-20030158151-A1 Fungicidal active ingredients combinations NAT1, PNMT, CYP1A1 HIF1A 4848/4885KLRK1 4826/4885MICA 3090/4885
US-20170265470-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 HIF1A 3943/4885KLRK1 4259/4885MICA 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.