SCHEMBL155385

SCHEMBL155385

CNC(=O)C(=NOC)c1ccccc1C=NOC(C)c1cccc(C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.36
KLRK1 P26718 2/20 0.35
MICA Q29983 2/20 0.35
RAET1L Q5VY80 2/20 0.35
NPSR1 Q6W5P4 1/20 0.34
KMT2A Q03164 4/20 0.34
HTT P42858 3/20 0.34
MEN1 O00255 3/20 0.34
POLB P06746 3/20 0.34
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
PTBP1 P26599 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ADAMTS4 O75173 1/20 0.34
MMP13 P45452 1/20 0.34
RXFP1 Q9HBX9 1/20 0.33
GAA P10253 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29645219 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL30416049 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL29459626 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL483329 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL8462213 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL154409 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL29716485 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL167138 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL8461974 1.00 HIF1A (0.36) HIF1AKLRK1MICARAET1LNPSR1
SCHEMBL14845758 0.90 CYP1A2 (0.36) HIF1AKLRK1MICARAET1LNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4361150-A2 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC Corporation (US) 2024-05-01 EP claimed
US-20240122180-A1 FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES FMC CORPORATION 2024-04-18 US claimed
US-20240090503-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION 2024-03-21 US claimed
US-20230413824-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2023-12-28 US claimed
EP-4262396-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION (US) 2023-10-25 EP claimed
CN-116801720-A Novel agrochemical compositions comprising 3-substituted benzamidine compounds and uses thereof 皮埃企业有限公司 2023-09-22 CN claimed
CN-116634874-A Fungicidal oxadiazoles and mixtures thereof FMC公司 2023-08-22 CN claimed
US-20230165251-A1 SUBSTITUTED TOLYL FUNGICIDES AND THEIR MIXTURES FMC CORPORATION 2023-06-01 US claimed
US-20230148599-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES FMC CORPORATION 2023-05-18 US claimed
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
WO-2001084931-A1 FUNGICIDAL COMBINATIONS OF ACTIVE AGENTS BAYER CROPSCIENCE AG (DE) 2001-11-15 WO claimed
WO-2001080641-A2 FUNGICIDAL ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2001-11-01 WO claimed
CN-1304288-A Fungicidal combinations containing glyoxylic acid methyl ester methyl oxime derivatives NOVARTIS AG (CH) 2001-07-18 CN claimed
WO-2001044215-A2 FUNGICIDAL COMBINATIONS OF ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2001-06-21 WO claimed
US-6235684-B1 SYNERGISTIC MIXTURE NOVARTIS CROP PROTECTION, INC. 2001-05-22 US claimed
US-20010000339-A1 Combating phytopathogenic diseases on crop plants by applying a synergistic mixture of 2-(alpha-((alpha-methyl-3-trifluoromethyl-benzyl)imino)-oxy)-o-tolyl) -glyoxalic acid, methyl ester O-methyloxime and various other fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2001-04-19 US claimed
EP-1085806-A2 FUNGICIDAL COMBINATIONS COMPRISING A GLYOXALIC ACID METHYLESTER METHYLOXIME DERIVATIVE Syngenta Participations AG (CH) 2001-03-28 EP claimed
EP-1006795-A1 FUNGICIDAL COMBINATIONS COMPRISING PHENYLACRYLIC ACID DERIVATIVES Novartis AG (CH) 2000-06-14 EP claimed
WO-1999063813-A2 FUNGICIDAL COMBINATIONS COMPRISING A GLYOXALIC ACID METHYLESTER METHYLOXIME DERIVATIVE NOVARTIS AG (CH) 1999-12-16 WO claimed
WO-1999011125-A1 FUNGICIDAL COMBINATIONS COMPRISING PHENYLACRYLIC ACID DERIVATIVES NOVARTIS AG (CH) 1999-03-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230413824-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF CBR3, PFAS, PAH HIF1A 2492/4885KLRK1 4350/4885MICA 3648/4885
US-20230148599-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES CYP1B1, CYP4B1, TH HIF1A 4833/4885KLRK1 4507/4885MICA 1968/4885
US-20010000339-A1 Combating phytopathogenic diseases on crop plants by applying a synergistic mixture of 2-(alpha-((alpha-methyl-3-trifluoromethyl-benzyl)imino)-oxy)-o-tolyl) -glyoxalic acid, methyl ester O-methyloxime and various other fungicides GLO1, AGXT, GNMT HIF1A 3234/4885KLRK1 4833/4885MICA 2551/4885
US-20240090503-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES NOX1, TH, NOX3 HIF1A 4722/4885KLRK1 4184/4885MICA 2051/4885
US-20240122180-A1 FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES AKR7A2, TBCA, TUBA1C HIF1A 3761/4885KLRK1 1184/4885MICA 739/4885
US-20230165251-A1 SUBSTITUTED TOLYL FUNGICIDES AND THEIR MIXTURES NAT1, TH, Q6ZSR9 HIF1A 4606/4885KLRK1 4524/4885MICA 2372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.