Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 4/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | RNMT | O43148 | 1/20 | 0.56 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.55 |
| ▸ | NNMT | P40261 | 2/20 | 0.55 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.55 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.55 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.55 |
| ▸ | INMT | O95050 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | PNMT | P11086 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | HNMT | P50135 | 1/20 | 0.55 |
| ▸ | WDR5 | P61964 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16715228 | 1.00 | MARS1 (0.63) | MARS1ADORA1RNMTDOT1LADORA3 | |
| SCHEMBL16715226 | 1.00 | MARS1 (0.63) | MARS1ADORA1RNMTDOT1LADORA3 | |
| SCHEMBL16715233 | 0.94 | MARS1 (0.72) | MARS1ADORA1RNMTDOT1LADORA3 | |
| SCHEMBL16715231 | 0.94 | MARS1 (0.72) | MARS1ADORA1RNMTDOT1LADORA3 | |
| SCHEMBL16715232 | 0.94 | MARS1 (0.72) | MARS1ADORA1RNMTDOT1LADORA3 | |
| SCHEMBL16715229 | 0.94 | MARS1 (0.72) | MARS1ADORA1RNMTDOT1LADORA3 | |
| SCHEMBL16715156 | 0.93 | ADORA1 (0.61) | MARS1ADORA1RNMTDOT1LADORA3 | |
| SCHEMBL16715152 | 0.93 | ADORA1 (0.61) | MARS1ADORA1RNMTDOT1LADORA3 | |
| SCHEMBL16715157 | 0.93 | ADORA1 (0.61) | MARS1ADORA1RNMTDOT1LADORA3 | |
| SCHEMBL16715166 | 0.87 | ADORA1 (0.64) | MARS1ADORA1RNMTDOT1LADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376700-B2 | Methods of modifying N-termini of a peptide or protein using transferases | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150140605-A1 | ONE STEP N-TERMINAL TAGGING OF PROTEINS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150140605-A1 | ONE STEP N-TERMINAL TAGGING OF PROTEINS | TRMT1, RNGTT, NSUN3 | MARS1 17/4885ADORA1 4442/4885RNMT 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.