Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.55 |
| ▸ | MOGAT2 | Q3SYC2 | 8/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16715485 | 0.89 | AR (0.54) | ARMOGAT2CARM1POLBTDP1 | |
| SCHEMBL15435172 | 0.89 | MOGAT2 (0.56) | MOGAT2POLBPRMT5WDR77MEN1 | |
| SCHEMBL15435408 | 0.85 | MOGAT2 (0.57) | MOGAT2MEN1PKMKMT2A | |
| SCHEMBL15435427 | 0.78 | MOGAT2 (0.63) | ARMOGAT2MEN1PKMKMT2A | |
| SCHEMBL15435378 | 0.77 | MOGAT2 (0.61) | MOGAT2MEN1KMT2A | |
| SCHEMBL16715492 | 0.75 | MOGAT2 (0.59) | MOGAT2MEN1KMT2A | |
| SCHEMBL15435035 | 0.75 | MOGAT2 (0.63) | ARMOGAT2MEN1PKMKMT2A | |
| SCHEMBL15435209 | 0.74 | MOGAT2 (0.63) | MOGAT2MEN1PKMKMT2A | |
| SCHEMBL15435191 | 0.74 | MOGAT2 (0.75) | MOGAT2 | |
| SCHEMBL15435212 | 0.73 | MOGAT2 (0.61) | MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |