Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682549 | 0.83 | BRD4 (0.35) | BRD4FTOERN1NPY2RHTT | |
| SCHEMBL1671580 | 0.82 | BRD4 (0.33) | BRD4FTOERN1 | |
| SCHEMBL1671582 | 0.82 | BRD4 (0.33) | BRD4FTOERN1 | |
| SCHEMBL11898521 | 0.79 | NPY2R (0.33) | BRD4FTOERN1NPY2R | |
| SCHEMBL1077880 | 0.79 | ALOX15 (0.37) | BRD4FTONPY2RMEN1USP2 | |
| SCHEMBL1035934 | 0.78 | FTO (0.35) | BRD4FTOERN1NPY2RALDH1A1 | |
| SCHEMBL1682455 | 0.78 | NPY2R (0.32) | BRD4FTONPY2R | |
| SCHEMBL11898664 | 0.76 | BRD4 (0.33) | BRD4FTOERN1HTT | |
| SCHEMBL11898894 | 0.73 | BRD4 (0.33) | BRD4FTO | |
| SCHEMBL1670490 | 0.71 | BRD4 (0.35) | BRD4ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |