SCHEMBL16716496

SCHEMBL16716496

CCNC(=O)N(C(=O)NCc1ccccc1)c1cnn(Cc2c(C)noc2C)c1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TAS2R8 Q9NYW2 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16716546 0.96 TAS2R8 (0.68) TAS2R8
SCHEMBL1279652 0.78 TAS2R8 (1.00) TAS2R8
SCHEMBL1278840 0.74 TAS2R8 (1.00) TAS2R8
SCHEMBL1279077 0.72 TAS2R8 (0.71) TAS2R8
SCHEMBL1279035 0.71 TAS2R8 (1.00) TAS2R8
SCHEMBL1278920 0.71 TAS2R8 (1.00) TAS2R8
SCHEMBL1278918 0.71 TAS2R8 (1.00) TAS2R8
SCHEMBL1279063 0.70 TAS2R8 (0.82) TAS2R8
SCHEMBL16716582 0.70 TAS2R8 (0.37) TAS2R8
SCHEMBL27811247 0.70 TAS2R8 (0.57) TAS2R8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2487169-B1 Compounds that inhibit (block) bitter taste in compositions and use thereof SENOMYX INC (US) 2015-05-20 — — EP disclosed
Send feedback