Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 19/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16716496 | 0.96 | TAS2R8 (0.64) | TAS2R8 | |
| SCHEMBL1279652 | 0.81 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1278840 | 0.77 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279077 | 0.74 | TAS2R8 (0.71) | TAS2R8 | |
| SCHEMBL1279035 | 0.74 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1278920 | 0.74 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1278918 | 0.74 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279063 | 0.73 | TAS2R8 (0.82) | TAS2R8 | |
| SCHEMBL16716582 | 0.73 | TAS2R8 (0.37) | TAS2R8MEN1KMT2A | |
| SCHEMBL27811247 | 0.73 | TAS2R8 (0.57) | TAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487169-B1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | SENOMYX INC (US) | 2015-05-20 | — | — | EP | disclosed |