Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 4/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16716546 | 0.73 | TAS2R8 (0.68) | TAS2R8KMT2AMEN1 | |
| SCHEMBL16716496 | 0.70 | TAS2R8 (0.64) | TAS2R8 | |
| SCHEMBL16716536 | 0.68 | CA12 (0.35) | KLKB1HPGDKMT2ACA12CA1 | |
| SCHEMBL16716547 | 0.64 | TAS2R8 (0.66) | TAS2R8 | |
| SCHEMBL7747829 | 0.61 | MTNR1A (0.36) | HPGDKMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL2854366 | 0.60 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL2860106 | 0.60 | KLKB1 (0.52) | KLKB1NPC1RAB9AL3MBTL1 | |
| SCHEMBL16716540 | 0.59 | TAS2R8 (0.64) | TAS2R8 | |
| SCHEMBL3362410 | 0.59 | HPGD (0.51) | HPGDKMT2ACA12CA1CA2 | |
| SCHEMBL27675547 | 0.59 | TP53 (0.49) | HPGDKMT2AMEN1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487169-B1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | SENOMYX INC (US) | 2015-05-20 | — | — | EP | disclosed |