Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979147 | 0.86 | MBOAT4 (0.46) | MBOAT4HRH4 | |
| SCHEMBL16699688 | 0.82 | MBOAT4 (0.53) | MBOAT4 | |
| SCHEMBL16699845 | 0.80 | MBOAT4 (0.49) | MBOAT4 | |
| SCHEMBL19979146 | 0.70 | MBOAT4 (0.59) | MBOAT4HRH4 | |
| SCHEMBL16699034 | 0.67 | MBOAT4 (0.63) | MBOAT4 | |
| SCHEMBL20009392 | 0.67 | MBOAT4 (0.60) | MBOAT4 | |
| SCHEMBL18166114 | 0.67 | MBOAT4 (0.66) | MBOAT4 | |
| SCHEMBL19971821 | 0.65 | MBOAT4 (0.64) | MBOAT4 | |
| SCHEMBL22661275 | 0.65 | HTT (0.34) | — | |
| SCHEMBL20009388 | 0.65 | MBOAT4 (0.38) | MBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068775-A1 | SUBSTITUTED PIPERIDYL-ETHYL-PYRIMIDINE AS GHRELIN O-ACYL TRANSFERASE INHIBITOR | Eli Lilly and Company (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073281-A1 | SUBSTITUTED PIPERIDYL-ETHYL-PYRIMIDINE AS GHRELIN O-ACYL TRANSFERASE INHIBITOR | ELI LILLY AND COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |