Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 12/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16718693 | 0.86 | MBOAT4 (0.44) | MBOAT4HRH4 | |
| SCHEMBL16699688 | 0.84 | MBOAT4 (0.53) | MBOAT4 | |
| SCHEMBL19979146 | 0.83 | MBOAT4 (0.59) | MBOAT4HRH4HRH3NCF1ACHE | |
| SCHEMBL16699845 | 0.80 | MBOAT4 (0.49) | MBOAT4 | |
| SCHEMBL18166114 | 0.69 | MBOAT4 (0.66) | MBOAT4 | |
| SCHEMBL20009392 | 0.69 | MBOAT4 (0.60) | MBOAT4 | |
| SCHEMBL19971821 | 0.67 | MBOAT4 (0.64) | MBOAT4 | |
| SCHEMBL20009388 | 0.67 | MBOAT4 (0.38) | MBOAT4HRH3 | |
| Hydrochloric Acid SCHEMBL16699518 | 0.66 | MBOAT4 (0.74) | MBOAT4 | |
| Hydrochloric Acid SCHEMBL19971786 | 0.66 | MBOAT4 (0.74) | MBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079729-A1 | GHRELIN 0-ACYL TRANSFERASE INHIBITORS | ELI LILLY AND COMPANY | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079729-A1 | GHRELIN 0-ACYL TRANSFERASE INHIBITORS | MBOAT4, GIPR, PLAAT2 | MBOAT4 1/4885HRH4 3601/4885HRH3 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.