⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27383371 | 1.00 | — | — | |
| SCHEMBL27383375 | 0.89 | DUT (0.33) | — | |
| SCHEMBL31614398 | 0.89 | DUT (0.31) | — | |
| SCHEMBL6778551 | 0.89 | DUT (0.31) | — | |
| SCHEMBL14965578 | 0.85 | BLM (0.41) | — | |
| SCHEMBL14966154 | 0.85 | KDM4E (0.31) | — | |
| SCHEMBL5320462 | 0.82 | LMNA (0.33) | — | |
| SCHEMBL14965387 | 0.81 | KDM4E (0.30) | — | |
| SCHEMBL31482290 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL15176109 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024025991-A1 | METHODS FOR DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION | THE METHODIST HOSPITAL SYSTEM (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2016050209-A1 | HETEROFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD, AND BIO-RELATED SUBSTANCE | 厦门赛诺邦格生物科技有限公司 | 2016-04-07 | — | — | WO | disclosed |
| US-20120302516-A1 | NANOPARTICLES FOR DRUG DELIVERY | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2012-11-29 | — | — | US | disclosed |
| EP-2490723-A1 | NANOPARTICLES FOR DRUG DELIVERY | University Of Louisville Research Foundation, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011049972-A1 | NANOPARTICLES FOR DRUG DELIVERY | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2011-04-28 | — | — | WO | disclosed |