Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965811 | 0.84 | CA12 (0.36) | SMN1; SMN2 | |
| SCHEMBL14965578 | 0.84 | BLM (0.41) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL1758843 | 0.83 | ALOX15 (0.41) | KDM4EMAPTALOX15SMN1; SMN2NR1D1 | |
| SCHEMBL27383371 | 0.81 | — | — | |
| SCHEMBL1671907 | 0.81 | — | — | |
| SCHEMBL5972996 | 0.81 | SIGMAR1 (0.30) | — | |
| SCHEMBL31614396 | 0.81 | — | — | |
| SCHEMBL3031948 | 0.79 | ALOX15 (0.41) | KDM4EMAPTALOX15SMN1; SMN2NR1D1 | |
| SCHEMBL14965532 | 0.79 | — | — | |
| SCHEMBL16298510 | 0.78 | CHRM5 (0.38) | KDM4EMAPTALOX15SMN1; SMN2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |