Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720111 | 0.82 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3145827 | 0.79 | SMN1; SMN2 (0.46) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29542545 | 0.77 | ALDH1A1 (0.53) | DDB1CRBNSIGMAR1MEN1KMT2A | |
| SCHEMBL3905172 | 0.77 | ALDH1A1 (0.53) | DDB1CRBNSIGMAR1MEN1KMT2A | |
| SCHEMBL695651 | 0.77 | ACHE (0.36) | DDB1CRBNSIGMAR1MEN1KMT2A | |
| SCHEMBL4802220 | 0.72 | DDB1 (0.43) | DDB1CRBNSIGMAR1MEN1KMT2A | |
| SCHEMBL692976 | 0.71 | EED (0.50) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5591602 | 0.71 | SCN9A (0.43) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL4859348 | 0.71 | MEN1 (0.31) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL1450385 | 0.71 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |