Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.38 |
| ▸ | LIPE | Q05469 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699695 | 0.89 | SCN9A (0.45) | SCN9ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL22719567 | 0.76 | SCN9A (0.48) | SCN9ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL29505029 | 0.76 | SCN9A (0.48) | SCN9ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL699190 | 0.74 | ALDH1A1 (0.44) | SCN9AMAPTDHFRNOTUMKDM4E | |
| SCHEMBL5591764 | 0.72 | SCN9A (0.40) | SCN9ANPC1RAB9ANOX4LIPE | |
| SCHEMBL15703756 | 0.72 | SCN9A (0.40) | SCN9ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL2091102 | 0.72 | SCN9A (0.55) | SCN9ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL16719802 | 0.71 | DDB1 (0.39) | NPC1RAB9AMAPK1L3MBTL1MEN1 | |
| SCHEMBL547971 | 0.71 | MAPT (0.41) | MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL22719524 | 0.70 | SLC6A9 (0.44) | SCN9ARAB9AMAPTMAPK1NOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076104-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2007-07-05 | — | — | WO | disclosed |