Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719997 | 0.83 | CNR1 (0.37) | CNR1CNR2 | |
| SCHEMBL16719523 | 0.79 | HSD17B1 (0.40) | KDM1AGAAABL1ABCB1BCR | |
| SCHEMBL16719911 | 0.79 | ALOX5 (0.49) | ABL1TSHRALOX5 | |
| SCHEMBL16720203 | 0.78 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL16719901 | 0.76 | ABL1 (0.44) | ABL1ABCB1BCRALOX5 | |
| SCHEMBL16719582 | 0.75 | HSD17B1 (0.47) | ALOX5 | |
| SCHEMBL16719772 | 0.74 | ESR2 (0.47) | TSHR | |
| SCHEMBL16719637 | 0.74 | ESR1 (0.42) | ABL1ABCB1BCRALOX5 | |
| SCHEMBL16719697 | 0.72 | CYP11B1 (0.42) | KDM1A | |
| SCHEMBL16719468 | 0.72 | KDM5A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |