Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 4/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294109 | 0.76 | QPCT (0.77) | QPCTQPCTLIDO1KDM4EALDH1A1 | |
| SCHEMBL6008269 | 0.74 | MAPT (0.50) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL31143361 | 0.74 | MAPT (0.50) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL16719750 | 0.74 | NPC1 (0.50) | NPC1 | |
| SCHEMBL28178021 | 0.72 | PARP1 (0.46) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL16719955 | 0.71 | GSK3B (0.53) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL28360929 | 0.71 | QPCT (0.47) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL16720439 | 0.71 | QPCT (0.50) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL2785993 | 0.71 | QPCT (0.37) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL16720494 | 0.71 | TYR (0.46) | KDM4EALDH1A1HPGDNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |