Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720128 | 0.74 | CYP1A1 (0.48) | CYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL16719934 | 0.73 | HSD17B1 (0.48) | HSD17B1CYP3A4 | |
| SCHEMBL16720028 | 0.73 | ATM (0.36) | — | |
| SCHEMBL9465979 | 0.67 | CYP2A6 (0.54) | CYP11B2CYP3A4 | |
| SCHEMBL3819587 | 0.65 | — | — | |
| SCHEMBL3338127 | 0.65 | — | — | |
| SCHEMBL9465196 | 0.64 | MAPT (0.46) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL28177242 | 0.63 | — | — | |
| SCHEMBL1026676 | 0.63 | HSD17B1 (0.55) | HSD17B1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL3601974 | 0.61 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |