Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551925 | 0.82 | BCL2 (0.45) | HPGDALOX15HSD17B10KEAP1 | |
| SCHEMBL10422126 | 0.78 | HTR1A (0.43) | ALDH1A1HPGDTDP1ALOX15MAOA | |
| SCHEMBL6271210 | 0.78 | TDP1 (0.34) | KDM4EALDH1A1HPGDTDP1ALOX15 | |
| SCHEMBL715204 | 0.77 | KCNH2 (0.41) | KDM4EALDH1A1HPGDTDP1ALOX15 | |
| SCHEMBL6753035 | 0.77 | MAOB (0.47) | ALDH1A1HPGDTDP1ALOX15MAOA | |
| SCHEMBL9359701 | 0.76 | CNR1 (0.35) | KDM4EALDH1A1HPGDTDP1ALOX15 | |
| SCHEMBL28157879 | 0.76 | TAAR1 (0.47) | KDM4EALDH1A1TDP1ALOX15HSD17B10 | |
| SCHEMBL16719748 | 0.74 | CA2 (0.32) | CA2 | |
| SCHEMBL5150284 | 0.74 | HTT (0.41) | ALDH1A1HPGDALOX15FFAR1MAOA | |
| SCHEMBL16719586 | 0.74 | KMT2A (0.47) | KDM4EALDH1A1MAOAMAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |