Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11925831 | 0.85 | ATM (0.66) | ALDH1A1ATMTSHRHPGDMGAM | |
| SCHEMBL2644442 | 0.78 | ALDH1A1 (1.00) | ALDH1A1ATMTSHRHPGDPOLB | |
| SCHEMBL10755428 | 0.77 | LMNA (0.62) | ALDH1A1ATMHPGDMGAMGAA | |
| SCHEMBL3729367 | 0.77 | ATM (1.00) | ALDH1A1ATMHPGDPOLBRAB9A | |
| Hydrogen Sulfide SCHEMBL28084028 | 0.77 | ALDH1A1 (0.96) | ALDH1A1ATMTSHRHPGDPOLB | |
| Methane SCHEMBL11192510 | 0.74 | TSHR (0.94) | ALDH1A1TSHRPOLB | |
| SCHEMBL10873457 | 0.74 | ATM (0.80) | ALDH1A1ATMHPGDPOLB | |
| SCHEMBL10821887 | 0.74 | GAA (0.60) | ALDH1A1ATMHPGDMGAMGAA | |
| SCHEMBL31421230 | 0.72 | ALDH1A1 (0.64) | ALDH1A1ATMHPGDL3MBTL1 | |
| SCHEMBL1313694 | 0.72 | KDM4E (0.56) | ALDH1A1ATMTSHRHPGDMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491045-B1 | 2-OXO-1-PYRROLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2015-12-23 | — | — | EP | disclosed |
| US-8822508-B2 | 2-oxo-1-pyrrolidinyl imidazothiadiazole derivatives | UCB PHARMA, S.A. (BE) | 2014-09-02 | — | — | US | disclosed |
| US-20120245208-A1 | 2-Oxo-1-Pyrrolidinyl Imidazothiadiazole Derivatives | UCB PHARMA, S.A. (BE) | 2012-09-27 | — | — | US | disclosed |
| EP-2491045-A1 | 2-OXO-1-PYRROLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB Pharma S.A. (BE) | 2012-08-29 | — | — | EP | disclosed |
| CN-102574869-A | 2-oxo-1-pyrrolidinyl imidazothiadiazole derivatives | UCB PHARMA SA | 2012-07-11 | — | — | CN | disclosed |
| WO-2011047860-A1 | 2-OXO-1-PYRROLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB PHARMA, S.A. (BE) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245208-A1 | 2-Oxo-1-Pyrrolidinyl Imidazothiadiazole Derivatives | CYP3A4, CYP3A43, CYP3A7 | ALDH1A1 620/4885ATM 3663/4885TSHR 3295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.