Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 4/20 | 0.63 |
| ▸ | RCE1 | Q9Y256 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930203 | 0.84 | LMNA (0.49) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL21842209 | 0.84 | RCE1 (0.58) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL14065375 | 0.82 | P4HB (0.63) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL21842238 | 0.78 | P4HB (0.74) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL21842470 | 0.78 | P4HB (0.59) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL21842239 | 0.78 | P4HB (0.74) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL12906706 | 0.78 | P4HB (0.55) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL11955293 | 0.77 | P4HB (1.00) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL21842473 | 0.77 | P4HB (0.81) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL21842240 | 0.76 | P4HB (0.70) | P4HBRCE1TP53CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178721-A1 | SUBSTITUTED N-BENZHYDRYLACETAMIDE INHIBITORS OF JUMANJI DOMAIN HISTONE DEMETHYLASES FOR THE TREATMENT OF CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2021-09-10 | — | — | WO | disclosed |
| WO-2015073836-A1 | COMPOSITIONS AND METHODS FOR TREATING CRYPTOSPORIDIOSIS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2015-05-21 | — | — | WO | disclosed |