Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 5/20 | 1.00 |
| ▸ | RCE1 | Q9Y256 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 5/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.84 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.80 |
| ▸ | HPGD | P15428 | 2/20 | 0.80 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11955279 | 0.91 | RCE1 (1.00) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL16501076 | 0.91 | RCE1 (0.84) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL23359134 | 0.89 | RCE1 (1.00) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL29962903 | 0.89 | RCE1 (1.00) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL11973553 | 0.89 | RCE1 (0.80) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL31741894 | 0.89 | RCE1 (1.00) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL31741895 | 0.89 | RCE1 (1.00) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL21842473 | 0.89 | P4HB (0.81) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL11955291 | 0.88 | RCE1 (0.78) | P4HBRCE1TP53CYP2C9CYP2C19 | |
| SCHEMBL11955287 | 0.88 | RCE1 (0.78) | P4HBRCE1TP53CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196853-A1 | Novel Quinoline-Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-02 | — | — | US | disclosed |
| US-20120196853-A1 | Novel Quinoline-Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196853-A1 | Novel Quinoline-Hepcidine Antagonists | HAMP, SLC40A1, FTH1 | P4HB 1974/4885RCE1 260/4885TP53 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.