Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | PTPRC | P08575 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16350809 | 0.92 | L3MBTL1 (0.72) | NPSR1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL13899725 | 0.92 | NPSR1 (0.67) | NPSR1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL19501628 | 0.89 | NPSR1 (0.63) | NPSR1L3MBTL1KDM4EMAPTLCK | |
| SCHEMBL1131584 | 0.88 | NPSR1 (0.67) | NPSR1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL30718955 | 0.88 | NPSR1 (0.67) | NPSR1L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL9123617 | 0.88 | NPSR1 (0.67) | NPSR1L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL11759504 | 0.88 | RAB9A (0.68) | NPSR1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL11873457 | 0.88 | NPSR1 (0.61) | NPSR1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL11878225 | 0.88 | NPSR1 (0.61) | NPSR1L3MBTL1KDM4EALDH1A1LCK | |
| SCHEMBL28419749 | 0.88 | NPSR1 (0.61) | NPSR1L3MBTL1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230541-A1 | PIPERAZINE DERIVATIVES USEFUL IN HIV THERAPY | VIIV HEALTHCARE COMPANY (US) | 2023-11-30 | — | — | WO | disclosed |
| US-9593197-B2 | Trigger-responsive chain-shattering polymers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-03-14 | — | — | US | disclosed |
| US-9593197-B2 | Trigger-responsive chain-shattering polymers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-03-14 | — | — | US | disclosed |
| US-20150141453-A1 | Trigger-Responsive Chain-Shattering Polymers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141453-A1 | Trigger-Responsive Chain-Shattering Polymers | SGTA, FUS, EWSR1 | NPSR1 2492/4885L3MBTL1 1786/4885KDM4E 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.