Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16723222 | 0.77 | TSHR (0.36) | HCRTR2KMT2AMEN1GAA | |
| SCHEMBL16723238 | 0.73 | SMN1; SMN2 (0.41) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL16723162 | 0.71 | IDH1 (0.37) | ALDH1A1GAA | |
| SCHEMBL16723104 | 0.69 | GAA (0.35) | GAA | |
| SCHEMBL16723248 | 0.69 | HSD11B1 (0.43) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL16722928 | 0.68 | HCRTR2 (0.32) | HCRTR2 | |
| SCHEMBL16722920 | 0.67 | HCRTR2 (0.34) | HCRTR2 | |
| SCHEMBL20643484 | 0.66 | HCRTR2 (0.46) | HCRTR2ALDH1A1 | |
| SCHEMBL16723246 | 0.66 | TSHR (0.64) | ALDH1A1GAA | |
| SCHEMBL16723230 | 0.65 | TSHR (0.37) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015074081-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BAIR KENNETH W (US) | 2015-05-21 | — | — | WO | disclosed |