Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16723391 | 0.83 | CHRM1 (0.38) | LMNAGAATSHRMAPTL3MBTL3 | |
| SCHEMBL16722934 | 0.81 | GAA (0.40) | GAATSHRMAPTMAPK1RECQL | |
| SCHEMBL16723166 | 0.78 | CHRNA7 (0.42) | LMNAMAPTL3MBTL3L3MBTL1SMN1; SMN2 | |
| SCHEMBL16723345 | 0.76 | GAA (0.36) | GAATSHRMAPTRECQL | |
| SCHEMBL16723237 | 0.75 | MAPT (0.40) | GAATSHRMAPT | |
| SCHEMBL16723321 | 0.73 | GAA (0.33) | GAATSHR | |
| SCHEMBL16723295 | 0.73 | GAA (0.37) | GAATSHRMAPTRECQL | |
| SCHEMBL16722992 | 0.72 | MAPT (0.38) | GAATSHRMAPT | |
| SCHEMBL16723361 | 0.72 | MAPT (0.37) | GAATSHRMAPT | |
| SCHEMBL16723246 | 0.70 | TSHR (0.64) | LMNAGAATSHRMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015074081-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BAIR KENNETH W (US) | 2015-05-21 | — | — | WO | disclosed |