Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 12/20 | 0.44 |
| ▸ | CDK2 | P24941 | 12/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 11/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 5/20 | 0.36 |
| ▸ | CCND1 | P24385 | 5/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.36 |
| ▸ | CDK1 | P06493 | 4/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639769 | 0.78 | CCNE1 (0.70) | CCNE1CDK2CCNE2GRM4CDK4 | |
| SCHEMBL9072653 | 0.72 | APEX1 (0.47) | CCNE1CDK2CCNE2APEX1ALDH1A1 | |
| SCHEMBL12466 | 0.72 | CCNE2 (0.58) | CCNE1CDK2CCNE2CDK4CCND1 | |
| SCHEMBL998883 | 0.69 | CCNE1 (0.43) | CCNE1CDK2CCNE2GRM4CDK4 | |
| SCHEMBL1000561 | 0.69 | CCNE1 (0.43) | CCNE1CDK2CCNE2GRM4CDK4 | |
| SCHEMBL1002462 | 0.69 | CCNE1 (0.43) | CCNE1CDK2CCNE2GRM4CDK4 | |
| SCHEMBL1000207 | 0.69 | CCNE1 (0.43) | CCNE1CDK2CCNE2GRM4CDK4 | |
| SCHEMBL1240028 | 0.69 | CCNE1 (0.46) | CCNE1CDK2CCNE2GRM4CDK4 | |
| SCHEMBL9094223 | 0.68 | APEX1 (0.42) | CCNE1CDK2CCNE2APEX1ALDH1A1 | |
| SCHEMBL2606483 | 0.67 | CDK2 (0.44) | CCNE1CDK2CCNE2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133218-B2 | Pesticidally active pyridyl- and pyrimidyl-substituted thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-15 | — | — | US | disclosed |
| US-20150141423-A1 | PESTICIDALLY ACTIVE PYRIDYL- AND PYRIMIDYL- SUBSTITUTED THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141423-A1 | PESTICIDALLY ACTIVE PYRIDYL- AND PYRIMIDYL- SUBSTITUTED THIAZOLE DERIVATIVES | PLPBP, DDT, PIR | CCNE1 2973/4885CDK2 401/4885CCNE2 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.