Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606389 | 0.83 | MYC (0.44) | MYCWDR5CDK2CSNK2A1SMN1; SMN2 | |
| SCHEMBL16724105 | 0.81 | SMN1; SMN2 (0.41) | MYCWDR5ALDH1A1CDK2SMN1; SMN2 | |
| SCHEMBL999731 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1CDK2SMN1; SMN2POLBHPGD | |
| SCHEMBL640218 | 0.79 | MYC (0.47) | MYCWDR5ALDH1A1CDK2CSNK2A1 | |
| SCHEMBL9094223 | 0.78 | APEX1 (0.42) | APEX1ALDH1A1CDK2CSNK2A1SMN1; SMN2 | |
| SCHEMBL1025059 | 0.76 | CDK2 (0.47) | MYCWDR5ALDH1A1CDK2CSNK2A1 | |
| SCHEMBL1025149 | 0.75 | MYC (0.47) | MYCWDR5ALDH1A1CDK2CSNK2A1 | |
| SCHEMBL13639769 | 0.74 | CCNE1 (0.70) | CDK2CCNE2CCNE1 | |
| SCHEMBL738352 | 0.73 | CDK2 (0.48) | MYCWDR5CDK2CSNK2A1SMN1; SMN2 | |
| SCHEMBL9258239 | 0.72 | APEX1 (0.46) | APEX1ALDH1A1CSNK2A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377856-A1 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2011-10-19 | — | — | EP | disclosed |
| WO-2007006760-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |