SCHEMBL1672459

SCHEMBL1672459

O=C(O)C1C2CCC(C1C(=O)O)C1C(=O)OC(=O)C21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.41
▸ LMNA P02545 3/20 0.41
▸ TDP1 Q9NUW8 3/20 0.41
▸ GMNN O75496 2/20 0.41
▸ TFPI2 P48307 2/20 0.41
▸ PMP22 Q01453 2/20 0.41
▸ TP53 P04637 2/20 0.41
▸ NFKB1 P19838 2/20 0.41
▸ THPO P40225 2/20 0.41
▸ PPM1B O75688 1/20 0.41
▸ PPP1CC P36873 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ PPP5C P53041 1/20 0.41
▸ PPP1CA P62136 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ TSHR P16473 1/20 0.38
▸ POLB P06746 3/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6321820 0.87 TDP1 (0.40) KDM4ELMNATDP1GMNNTFPI2
SCHEMBL24084126 0.81 KDM4E (0.40) KDM4ELMNATDP1GMNNTFPI2
SCHEMBL3137226 0.79 EDNRB (0.39) KDM4ELMNATDP1GMNNTFPI2
SCHEMBL31509894 0.79 KDM4E (0.39) KDM4ELMNATDP1GMNNTFPI2
SCHEMBL8918724 0.79 KDM4E (0.39) KDM4ELMNATDP1GMNNTFPI2
SCHEMBL722306 0.78 KDM4E (0.55) KDM4ELMNATDP1GMNNTFPI2
SCHEMBL4570299 0.78 KDM4E (0.55) KDM4ELMNATDP1GMNNTFPI2
SCHEMBL21338787 0.78 KDM4E (0.55) KDM4ELMNATDP1GMNNTFPI2
SCHEMBL10080802 0.78 KDM4E (0.55) KDM4ELMNATDP1GMNNTFPI2
SCHEMBL15498551 0.78 KDM4E (0.55) KDM4ELMNATDP1GMNNTFPI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1930382-B1 COATING MATERIALS CONSISTING OF LOW- OR MEDIUM-MOLECULAR ORGANIC COMPOUNDS CENTRAL GLASS CO LTD (JP) 2011-07-27 — — EP disclosed
US-7919224-B2 Coating materials consisting of low- or medium-molecular organic compounds CENTRAL GLASS COMPANY, LIMITED (JP) 2011-04-05 — — US disclosed
US-20090272295-A1 Coating Materials Consisting of Low- or Medium-Molecular Organic Compounds CENTRAL GLASS COMPANY, LIMITED (JP) 2009-11-05 — — US disclosed
US-7517635-B2 Polyester compound and resist material using the same CENTRAL GLASS COMPANY, LIMITED (JP) 2009-04-14 — — US disclosed
EP-1930382-A1 COATING MATERIALS CONSISTING OF LOW- OR MEDIUM-MOLECULAR ORGANIC COMPOUNDS Central Glass Company, Limited (JP) 2008-06-11 — — EP disclosed
US-20080050674-A1 Polyester compound and resist material using the same CENTRAL GLASS COMPANY, LIMITED (JP) 2008-02-28 — — US disclosed
WO-2007037101-A1 COATING MATERIALS CONSISTING OF LOW- OR MEDIUM-MOLECULAR ORGANIC COMPOUNDS CENTRAL GLASS COMPANY, LIMITED (JP) 2007-04-05 — — WO disclosed
JP-2007002045-A POLYESTER COMPOUND AND RESIST MATERIAL GIVEN BY USING THE SAME CENTRAL GLASS CO LTD 2007-01-11 — — JP disclosed
EP-0639612-A1 High viscosity polyester compositions ENICHEM S.p.A. (IT) 1995-02-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090272295-A1 Coating Materials Consisting of Low- or Medium-Molecular Organic Compounds OXGR1, OXER1, BHMT2 KDM4E 920/4885LMNA 3990/4885TDP1 4255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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