Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GMNN | O75496 | 2/20 | 0.37 |
| ▸ | TFPI2 | P48307 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | THPO | P40225 | 2/20 | 0.37 |
| ▸ | PPM1B | O75688 | 2/20 | 0.37 |
| ▸ | PPP5C | P53041 | 2/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672459 | 0.87 | KDM4E (0.41) | TDP1POLBMAPK1LMNAKDM4E | |
| SCHEMBL13957510 | 0.84 | POLB (0.32) | TDP1POLBMAPK1PPM1B | |
| SCHEMBL7857014 | 0.82 | HSD11B1 (0.34) | TDP1POLBLMNAHTT | |
| SCHEMBL3137226 | 0.79 | EDNRB (0.39) | TDP1POLBLMNAKDM4EGMNN | |
| SCHEMBL8918724 | 0.79 | KDM4E (0.39) | TDP1POLBLMNAKDM4EGMNN | |
| SCHEMBL31509894 | 0.79 | KDM4E (0.39) | TDP1POLBLMNAKDM4EGMNN | |
| SCHEMBL721779 | 0.78 | KDM4E (0.48) | TDP1LMNAKDM4EGMNNTFPI2 | |
| SCHEMBL19287328 | 0.78 | KDM4E (0.48) | TDP1LMNAKDM4EGMNNTFPI2 | |
| SCHEMBL14675352 | 0.77 | LMNA (0.35) | TDP1POLBMAPK1LMNAKDM4E | |
| SCHEMBL9994809 | 0.77 | EDNRB (0.38) | TDP1LMNAKDM4EGMNNTFPI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050058619-A1 | Polyether-modified polymers as leather auxiliaries | LANXESS DEUTSCHLAND GMBH (DE) | 2005-03-17 | — | — | US | claimed |
| US-20050058619-A1 | Polyether-modified polymers as leather auxiliaries | LANXESS DEUTSCHLAND GMBH (DE) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050058619-A1 | Polyether-modified polymers as leather auxiliaries | PUF60, B2M, CBR3 | TDP1 4570/4885POLB 1986/4885MAPK1 2758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.