Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.49 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.49 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.49 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771282 | 0.89 | USP2 (0.55) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL14405371 | 0.88 | USP2 (0.54) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL21059437 | 0.88 | LGALS9 (0.55) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL14356282 | 0.86 | LGALS9 (0.54) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL8394105 | 0.86 | POLB (0.49) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL8391343 | 0.86 | POLB (0.49) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL20143480 | 0.85 | PTPN1 (0.55) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL21007943 | 0.85 | PTPN1 (0.55) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL14477068 | 0.85 | PTPN1 (0.55) | POLBMEN1USP2KMT2ALGALS9 | |
| SCHEMBL20693186 | 0.85 | PTPN1 (0.55) | POLBMEN1USP2KMT2ALGALS9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605018-B2 | Substituted nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-20150141363-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141363-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | PNP, NUDT1, TYMP | POLB 79/4885MEN1 1839/4885USP2 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.