Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | HEXA | P06865 | 2/20 | 0.63 |
| ▸ | HEXB | P07686 | 2/20 | 0.63 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15923444 | 0.94 | HTR1A (0.63) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL10050510 | 0.87 | RAB9A (0.85) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL15923353 | 0.86 | MAPT (0.67) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL2205237 | 0.84 | RAB9A (0.71) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL2204905 | 0.84 | RAB9A (0.71) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL16726539 | 0.83 | RAB9A (0.62) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL17334640 | 0.83 | RAB9A (0.62) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL7299163 | 0.83 | RAB9A (1.00) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL10960255 | 0.83 | RAB9A (0.70) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL10677584 | 0.83 | RAB9A (0.75) | RAB9AMAPTSMN1; SMN2TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044208-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2017-02-16 | — | — | US | disclosed |
| US-20170044208-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2017-02-16 | — | — | US | disclosed |
| WO-2015071657-A9 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2016-09-15 | — | — | WO | disclosed |
| WO-2015071657-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | THE UNIVERSITY OF MANCHESTER (GB) | 2015-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044208-A1 | SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS | NR3C1, NR3C2, NR5A1 | RAB9A 3557/4885MAPT 4838/4885SMN1; SMN2 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.