Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.46 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.44 |
| ▸ | GAPDH | P04406 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20485764 | 1.00 | HIF1A (0.48) | HIF1AHSPA5HSPA8DOT1LGAPDH | |
| SCHEMBL20434908 | 1.00 | HIF1A (0.48) | HIF1AHSPA5HSPA8DOT1LGAPDH | |
| SCHEMBL3301022 | 1.00 | HIF1A (0.48) | HIF1AHSPA5HSPA8DOT1LGAPDH | |
| SCHEMBL16715133 | 1.00 | HIF1A (0.48) | HIF1AHSPA5HSPA8DOT1LGAPDH | |
| SCHEMBL29325495 | 1.00 | HIF1A (0.48) | HIF1AHSPA5HSPA8DOT1LGAPDH | |
| SCHEMBL25495855 | 1.00 | HIF1A (0.48) | HIF1AHSPA5HSPA8DOT1LGAPDH | |
| SCHEMBL29323405 | 1.00 | HIF1A (0.48) | HIF1AHSPA5HSPA8DOT1LGAPDH | |
| SCHEMBL17130296 | 1.00 | HIF1A (0.48) | HIF1AHSPA5HSPA8DOT1LGAPDH | |
| SCHEMBL15548668 | 0.83 | ADK (0.44) | HIF1ADOT1LGAPDHADORA3DPP4 | |
| SCHEMBL866579 | 0.82 | ATG7 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238323-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | EMORY UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| EP-2854813-B1 | PYRAZOLOTRIAZOLYL NUCLEOSIDE ANALOGUES AND OLIGONUCLEOTIDES COMPRISING THEM | BIO LAB LTD (IL) | 2018-07-25 | — | — | EP | disclosed |
| US-9994604-B2 | Pyrazolotriazolyl nucleoside analogues and oligonucleotides comprising them | BIO-LAB LTD. (IL) | 2018-06-12 | — | — | US | disclosed |
| US-9994604-B2 | Pyrazolotriazolyl nucleoside analogues and oligonucleotides comprising them | BIO-LAB LTD. (IL) | 2018-06-12 | — | — | US | disclosed |
| US-20150141490-A1 | PYRAZOLOTRIAZOLYL NUCLEOSIDE ANALOGUES AND OLIGONUCLEOTIDES COMPRISING THEM | BIO-LAB LTD. (IL) | 2015-05-21 | — | — | US | disclosed |
| US-20150141490-A1 | PYRAZOLOTRIAZOLYL NUCLEOSIDE ANALOGUES AND OLIGONUCLEOTIDES COMPRISING THEM | BIO-LAB LTD. (IL) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141490-A1 | PYRAZOLOTRIAZOLYL NUCLEOSIDE ANALOGUES AND OLIGONUCLEOTIDES COMPRISING THEM | NT5C2, TK2, DUT | HIF1A 4335/4885HSPA5 1792/4885HSPA8 2843/4885 |
| US-20240238323-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | MTAP, PNP, SARS1 | HIF1A 532/4885HSPA5 3449/4885HSPA8 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.