Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960410 | 0.86 | TAS1R3 (0.47) | TAS1R3TAS1R1HSD17B1MAPK1LMNA | |
| SCHEMBL15492066 | 0.85 | PKM (0.44) | PKMMAPK1LMNAPOLBHTT | |
| SCHEMBL13361795 | 0.84 | PKM (0.52) | HSD17B1PKMMAPK1POLBHTT | |
| SCHEMBL17198001 | 0.84 | TSHR (0.61) | TAS1R3TAS1R1MAPK1LMNANLRP1 | |
| SCHEMBL4810977 | 0.83 | PKM (0.47) | HSD17B1PKMMAPK1LMNAPOLB | |
| SCHEMBL4814551 | 0.83 | PKM (0.43) | PKMLMNAPOLBHTTKMT2A | |
| SCHEMBL1696442 | 0.82 | SLC6A4 (0.50) | TAS1R3TAS1R1MAPK1LMNANLRP1 | |
| SCHEMBL27015334 | 0.82 | TAS1R3 (0.44) | TAS1R3TAS1R1HSD17B1MAPK1LMNA | |
| SCHEMBL4090026 | 0.82 | HPGD (0.44) | PKMLMNAHTTKMT2AMAPT | |
| SCHEMBL3279437 | 0.81 | PKM (0.57) | HSD17B1PKMPOLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073767-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |