Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960410 | 0.84 | TAS1R3 (0.47) | TAS1R3TAS1R1LMNAMAPK1NLRP1 | |
| SCHEMBL16728864 | 0.82 | TAS1R3 (0.49) | TAS1R3TAS1R1LMNAMAPK1NLRP1 | |
| SCHEMBL1362391 | 0.82 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1HSD17B1MEN1HTT | |
| SCHEMBL16951562 | 0.81 | TAS1R3 (0.43) | TAS1R3TAS1R1LMNAMAPK1NLRP1 | |
| SCHEMBL25531544 | 0.80 | TAS1R3 (0.42) | TAS1R3TAS1R1LMNAMAPK1NLRP1 | |
| SCHEMBL16957376 | 0.79 | TAS1R3 (0.43) | TAS1R3TAS1R1LMNAMAPK1NLRP1 | |
| SCHEMBL19291095 | 0.78 | HSD17B1 (0.40) | LMNAHSP90AA1HSP90AB1EPHX2HSD17B1 | |
| SCHEMBL17198001 | 0.78 | TSHR (0.61) | TAS1R3TAS1R1LMNAMAPK1NLRP1 | |
| SCHEMBL10336411 | 0.78 | HSD17B1 (0.43) | HSP90AA1HSP90AB1HSD17B1HTTPOLB | |
| SCHEMBL16956386 | 0.78 | TAS1R3 (0.43) | TAS1R3TAS1R1LMNAMAPK1NLRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | STAT4, STAT1, STAT3 | TAS1R3 3999/4885TAS1R1 4104/4885LMNA 4438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.