Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539198 | 1.00 | P2RX7 (0.53) | P2RX7FAAHCNR1CNR2SGMS2 | |
| SCHEMBL16730194 | 0.91 | KMT2A (0.50) | P2RX7FAAHCNR1CNR2SGMS2 | |
| SCHEMBL15552978 | 0.91 | KMT2A (0.50) | P2RX7FAAHCNR1CNR2SGMS2 | |
| SCHEMBL16730225 | 0.91 | P2RX7 (0.53) | P2RX7FAAHCNR1CNR2ABCB1 | |
| SCHEMBL15539903 | 0.91 | P2RX7 (0.53) | P2RX7FAAHCNR1CNR2ABCB1 | |
| SCHEMBL15539925 | 0.90 | MAPT (0.48) | P2RX7FAAHCNR1CNR2SGMS2 | |
| SCHEMBL16730189 | 0.90 | MAPT (0.48) | P2RX7FAAHCNR1CNR2SGMS2 | |
| SCHEMBL15539818 | 0.89 | ABCB1 (0.52) | P2RX7FAAHCNR1CNR2ABCB1 | |
| SCHEMBL16730190 | 0.89 | ABCB1 (0.52) | P2RX7FAAHCNR1CNR2ABCB1 | |
| SCHEMBL15540454 | 0.87 | P2RX7 (0.59) | P2RX7FAAHCNR2ABCB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2016-11-03 | — | — | US | disclosed |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSTÄT WIEN (AT) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | P2RX7 1877/4885FAAH 1123/4885CNR1 142/4885 |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | P2RX7 1877/4885FAAH 1123/4885CNR1 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.