SCHEMBL1673203

SCHEMBL1673203

Clc1ccnc(-c2ccccc2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
HTT P42858 1/20 0.45
MAPT P10636 4/20 0.43
PTK2B Q14289 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
POLB P06746 3/20 0.42
KDM4E B2RXH2 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPK1 P28482 1/20 0.42
SMO Q99835 2/20 0.42
ATP4A P20648 1/20 0.42
ATP4B P51164 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
ABCG2 Q9UNQ0 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRG2 P18507 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28483238 0.96 LMNA (0.47) LMNAKMT2AMEN1HTTMAPT
Methyl Alcohol SCHEMBL10573082 0.94 LMNA (0.50) LMNAKMT2AMEN1HTTMAPT
SCHEMBL2650448 0.83 L3MBTL1 (0.49) LMNAKMT2AMEN1HTTMAPT
SCHEMBL2132620 0.83 MAPT (0.59) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL30061028 0.83 L3MBTL1 (0.49) LMNAKMT2AMEN1HTTMAPT
SCHEMBL29240027 0.81 CYP2A6 (0.39) LMNAKMT2AMEN1HTTMAPT
SCHEMBL15966607 0.80 CYP2A6 (0.62) LMNAKMT2AHTTMAPTPOLB
SCHEMBL8344326 0.80 CYP19A1 (0.54) MAPTNPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL22042784 0.80 KDM4E (0.53) LMNAKMT2AMEN1MAPTPTK2B
SCHEMBL16698710 0.80 HSD17B1 (0.42) LMNAKMT2AMEN1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 660 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105580692-A Efficient cultivation method of ornamental maple trees ZHOU BO 2016-05-18 CN claimed
CN-101160049-B Spiroketal-substituted cyclic ketoenols BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-05-11 CN claimed
CN-105028414-A HERBICIDE-SAFENER COMBINATION BAYER IP GMBH 2015-11-11 CN claimed
CN-104761521-A Biphenyl-Substituted Spirocyclic Ketoenols BAYER CROPSCIENCE AG 2015-07-08 CN claimed
CN-103396404-B Compound using triphenylpyrimidine as core as well as preparation method and application thereof UNIV SOUTH CHINA TECH 2015-04-22 CN claimed
CN-102675315-B Substitutive benzene alkyl contained purine compounds and preparation method and application thereof FOURTH MILITARY MEDICAL UNIV 2015-04-01 CN claimed
CN-104320972-A Herbicidal composition comprising uracil compound as active ingredient DONGBU FARM HANNONG CO LTD 2015-01-28 CN claimed
CN-102246790-B Novel herbicides based on substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(thi)ones and 4-hppd-inhibitors BAYER CROPSCIENCE AG 2014-08-20 CN claimed
CN-101568522-B Trifluoromethoxyphenyl-substituted tetramic acid derivatives as pesticides and/or herbicides BAYER CROPSCIENCE AG 2014-05-14 CN claimed
CN-103755716-A Spiroketal-substituted cyclic ketoenols BAYER CROPSCIENCE AG 2014-04-30 CN claimed
CN-1264274-A Herbicidal compositions of tetrazolinone herbicides and antidotes therefor ZENECA LTD (GB) 2000-08-23 CN claimed
CN-1044069-C Softening imidazolinone herbicides MONSANTO CO (US) 1999-07-14 CN claimed
CN-1168083-A Herbicidal composition of 4-benzoylisoxazole or 2-cyano-1,3-dione herbicides and antidotes therefor ZENECA LTD (GB) 1997-12-17 CN claimed
CN-1155381-A Synergistic herbicidal composition and method for controlling weeds CIBA GEIGY AG (CH) 1997-07-30 CN claimed
CN-1081815-A Safe with pyrazolyl sulfonylureas of activity of weeding MONSANTO CO (US) 1994-02-16 CN claimed
CN-1063015-A Safe herbicidal sulfonamide compositions MONSANTO CO (US) 1992-07-29 CN claimed
CN-1061322-A The safe of benzoic acid derivative class weed killer herbicide MONSANTO CO (US) 1992-05-27 CN claimed
CN-1052768-A The safe handling of imidazolidinone weedicide MONSANTO CO (US) 1991-07-10 CN claimed
CN-1039949-A The protection of benzoic acid derivative class weed killer herbicide MONSANTO CO (US) 1990-02-28 CN claimed
CN-87102879-A Benzhydryl compounds as herbicide antidotes 1987-10-28 CN claimed