Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28117121 | 0.85 | LMNA (0.50) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL1425524 | 0.85 | — | — | |
| E968 SCHEMBL21173668 | 0.82 | LMNA (0.47) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| E968 SCHEMBL28654266 | 0.82 | LMNA (0.47) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| E968 SCHEMBL28649789 | 0.82 | LMNA (0.47) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL9585355 | 0.82 | — | — | |
| Phosphoric Acid SCHEMBL7091040 | 0.78 | USP2 (0.39) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| Mannitol SCHEMBL3887158 | 0.77 | LMNA (0.69) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| Adonitol SCHEMBL20481269 | 0.77 | LMNA (0.59) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| Mannitol SCHEMBL20572201 | 0.77 | LMNA (0.69) | USP2SLCO1B1LMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479776-B2 | Expression system | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2022-10-25 | — | — | US | disclosed |
| US-20210002653-A1 | Expression System | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2021-01-07 | — | — | US | disclosed |
| US-10465220-B2 | Expression process | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2019-11-05 | — | — | US | disclosed |
| US-20180057823-A1 | Expression Vector | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2018-03-01 | — | — | US | disclosed |
| US-9845475-B2 | Expression vector | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2017-12-19 | — | — | US | disclosed |
| US-9677104-B2 | Expression process | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2017-06-13 | — | — | US | disclosed |
| US-20160024509-A1 | Expression Vector | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2016-01-28 | — | — | US | disclosed |
| US-9157085-B2 | Expression vector for expression of eukaryotic secretion leader sequence fused with a target polypeptide and methods of use thereof | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2015-10-13 | — | — | US | disclosed |
| WO-2015071623-A1 | USE OF METE GENE AS AUXOTROPHIC MARKER IN GENETIC CONSTRUCTS | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2015-05-21 | — | — | WO | disclosed |
| US-20140370543-A1 | Expression Process | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2014-12-18 | — | — | US | disclosed |
| US-20130273605-A1 | Expression Process | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2013-10-17 | — | — | US | disclosed |
| US-20110086391-A1 | Expression Vector | FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED (GB) | 2011-04-14 | — | — | US | disclosed |