Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 11/20 | 0.59 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.57 |
| ▸ | HTR3B | O95264 | 3/20 | 0.57 |
| ▸ | HTR3A | P46098 | 3/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784241 | 0.80 | CHKA (0.52) | ALDH1A1KDM4EUSP2HSD17B10 | |
| SCHEMBL5570604 | 0.79 | ADRB1 (0.77) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8161762 | 0.79 | ADRB1 (0.57) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7717270 | 0.79 | ADRB1 (0.57) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL25803365 | 0.79 | ADRB1 (0.53) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL17327846 | 0.78 | CHKA (0.53) | ALDH1A1KDM4EUSP2HSD17B10 | |
| Water SCHEMBL15212791 | 0.78 | CHKA (0.50) | ALDH1A1KDM4EUSP2HSD17B10 | |
| Iodide SCHEMBL15212223 | 0.78 | CHKA (0.50) | ALDH1A1KDM4EUSP2HSD17B10 | |
| SCHEMBL81940 | 0.74 | ADRB1 (1.00) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6645952 | 0.74 | ADRB1 (1.00) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030096-B2 | Water-soluble rhodamine dyes conjugates | APPLIED BIOSYSTEMS LLC (US) | 2011-10-04 | — | — | US | disclosed |
| US-20110081688-A1 | Water-Soluble Rhodamine Dyes Conjugates | Life Technologies Corporation (US) | 2011-04-07 | — | — | US | disclosed |
| US-7795042-B2 | Water-soluble rhodamine dye conjugates | APPLIED BIOSYSTEMS, LLC (US) | 2010-09-14 | — | — | US | disclosed |
| US-7696354-B2 | Cephem compounds having broad antibacterial spectrum | SHIONOGI & CO., LTD. (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20090305433-A1 | Water-Soluble Rhodamine Dye Conjugates | APPLIED BIOSYSTEMS INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090131655-A1 | Cephem Compounds Having Broad Antibacterial Spectrum | SHIONOGI & CO., LTD. | 2009-05-21 | — | — | US | disclosed |
| US-7504496-B2 | Water-soluble rhodamine dye conjugates | APPLIED BIOSYSTEMS, LLC | 2009-03-17 | — | — | US | disclosed |
| US-7384928-B2 | Broad spectrum cephem compounds | SHIONOGI & CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-7384928-B2 | Broad spectrum cephem compounds | SHIONOGI & CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-20050153355-A1 | Water-soluble rhodamine dye conjugates | APPLERA CORPORATION (US) | 2005-07-14 | — | — | US | disclosed |
| US-20030055257-A1 | Water-soluble rhodamine dye conjugates | APPLERA CORPORATION (US) | 2003-03-20 | — | — | US | disclosed |
| US-6372907-B1 | LABELLED RHODAMINE DYE-POLYPEPTIDE CONJUGATE, OR SALT THEREOF, COMPRISING RHODAMINE-TYPE PARENT XANTHENE RING SUBSTITUTED AT XANTHENE C-9 CARBON WITH SUBSTITUTED PHENYL RING | APPTERA CORPORATION | 2002-04-16 | — | — | US | disclosed |
| EP-1141137-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | Applera Corporation (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001032783-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | APPLERA CORPORATION (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6191278-B1 | COMPRISING A RHODAMINE-TYPE PARENT RING HAVING ATTACHED TO THE XANTHENE C9 CARBON A PHENYL GROUP THAT IS SUBSTITUTED WITH CARBOXY OR SULFONATE GROUP, ONE TO THREE AMINOPYRIDINIUM GROUPS AND AN ALKYL- OR ARYLTHIO, AND OPTIONALLY OTHER GROUPS | PE CORPORATION | 2001-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153355-A1 | Water-soluble rhodamine dye conjugates | SLC43A3, ABCG2, TARBP1 | ADRB1 3264/4885HTR3E 3573/4885HTR3B 4011/4885 |
| US-20090131655-A1 | Cephem Compounds Having Broad Antibacterial Spectrum | ZYX, NAT10, NAA50 | ADRB1 3284/4885HTR3E 4629/4885HTR3B 4518/4885 |
| US-20030055257-A1 | Water-soluble rhodamine dye conjugates | SLC43A3, ABCG2, TARBP1 | ADRB1 3264/4885HTR3E 3573/4885HTR3B 4011/4885 |
| US-20090305433-A1 | Water-Soluble Rhodamine Dye Conjugates | SLC43A3, ABCG2, TARBP1 | ADRB1 3264/4885HTR3E 3573/4885HTR3B 4011/4885 |
| US-20110081688-A1 | Water-Soluble Rhodamine Dyes Conjugates | SLC43A3, ABCG2, TARBP1 | ADRB1 3352/4885HTR3E 3614/4885HTR3B 4024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.