Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2869309 | 1.00 | ACE (0.33) | ACE | |
| SCHEMBL3660712 | 0.83 | LMNA (0.32) | — | |
| SCHEMBL3392097 | 0.77 | ACE (0.33) | ACE | |
| SCHEMBL17495292 | 0.75 | MAPK1 (0.39) | — | |
| SCHEMBL5420095 | 0.75 | HSD17B10 (0.42) | — | |
| SCHEMBL3274371 | 0.74 | LMNA (0.33) | — | |
| SCHEMBL17510318 | 0.74 | LMNA (0.33) | — | |
| SCHEMBL25364590 | 0.74 | ABAT (0.34) | ACE | |
| SCHEMBL22636529 | 0.74 | ACE (0.32) | ACE | |
| SCHEMBL22636530 | 0.74 | ACE (0.32) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758480-B2 | 1-(cycloalkyl-carbonyl)proline derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9718840-B2 | Condensed 5-oxazolidinone derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-20170022218-A1 | CONDENSED 5-OXAZOLIDINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2017-01-26 | — | — | US | disclosed |
| EP-3095786-A1 | CONDENSED 5-OXAZOLIDINONE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2016-11-23 | — | — | EP | disclosed |
| US-20150210640-A1 | 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2015-07-30 | — | — | US | disclosed |
| EP-2876105-A1 | 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2015-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210640-A1 | 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE | RB1, F2, SFPQ | ACE 1608/4885 |
| US-20170022218-A1 | CONDENSED 5-OXAZOLIDINONE DERIVATIVE | F2, SERPINC1, F12 | ACE 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.