SCHEMBL16735446

SCHEMBL16735446

C=CC[Si]1(CC=C)c2cc(B3OC(C)(C)C(C)(C)O3)ccc2-c2ccc(B3OC(C)(C)C(C)(C)O3)cc21

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.40
LPL P06858 13/20 0.40
F11 P03951 1/20 0.35
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
ESR2 Q92731 1/20 0.33
CA12 O43570 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
CSF1R P07333 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17742883 0.88 LPL (0.33) LIPGLPL
SCHEMBL14816705 0.78 LIPG (0.44) LIPGLPLF11CA1CA2
SCHEMBL15257233 0.74 LIPG (0.54) LIPGLPLF11PRMT5WDR77
SCHEMBL14371925 0.74 LIPG (0.54) LIPGLPLF11PRMT5WDR77
SCHEMBL14790083 0.74 LIPG (0.54) LIPGLPLF11PRMT5WDR77
SCHEMBL12131317 0.74 LIPG (0.54) LIPGLPLF11PRMT5WDR77
SCHEMBL9987725 0.73 LIPG (0.40) LIPGLPLF11PRMT5WDR77
SCHEMBL19299637 0.72 LPL (0.42) LIPGLPLF11PRMT5WDR77
SCHEMBL31187004 0.72 LIPG (0.46) LIPGLPLPRMT5WDR77CA1
SCHEMBL31757597 0.72 LIPG (0.46) LIPGLPLPRMT5WDR77CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2657239-B1 ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHODS AND USES THEREOF OCEANS KING LIGHTING SCIENCE (CN) 2015-05-27 EP claimed
US-10570250-B2 Dibenzosilole monomers and polymers and methods for their preparation and use Life Technologies Corporation (US) 2020-02-25 US disclosed
US-20170247504-A1 DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE Life Technologies Corporation 2017-08-31 US disclosed
US-20170247504-A1 DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE Life Technologies Corporation 2017-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570250-B2 Dibenzosilole monomers and polymers and methods for their preparation and use DDOST, DDT, DAD1 LIPG 1120/4885LPL 2544/4885F11 979/4885
US-20170247504-A1 DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE DDOST, DDT, DAD1 LIPG 1120/4885LPL 2544/4885F11 979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.