Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 7/20 | 0.46 |
| ▸ | CFTR | P13569 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735575 | 0.82 | HSP90AA1 (0.58) | PDK1ALDH1A1PDK2PDK3PDK4 | |
| SCHEMBL16735606 | 0.78 | PDK1 (0.47) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL2143912 | 0.78 | EGLN1 (0.57) | L3MBTL1CFTRTSHRALDH1A1 | |
| SCHEMBL16735626 | 0.74 | PDK1 (0.46) | PDK1CYP3A4PDK2PDK3PDK4 | |
| SCHEMBL16735638 | 0.74 | MAOB (0.47) | L3MBTL1PDK1TSHRPDK2MEN1 | |
| SCHEMBL9804179 | 0.74 | MAPT (0.54) | L3MBTL1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL16735595 | 0.74 | MET (0.54) | PDK1CYP3A4TSHRALDH1A1KMT2A | |
| SCHEMBL28336465 | 0.73 | MCL1 (0.66) | L3MBTL1CYP3A4TSHRALDH1A1MEN1 | |
| SCHEMBL16735588 | 0.73 | HSP90AA1 (0.52) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL16735599 | 0.73 | PDK1 (0.51) | L3MBTL1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |