Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526849 | 0.72 | COPS5 (0.61) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL3264169 | 0.71 | KDM4E (0.62) | PIM1LMNAMEN1KMT2A | |
| SCHEMBL2297701 | 0.71 | CHEK2 (0.35) | ALDH1A1LMNARAB9AMEN1KMT2A | |
| SCHEMBL3920912 | 0.70 | MEN1 (0.64) | HDAC3HDAC1HDAC2HDAC8HPGD | |
| SCHEMBL12472546 | 0.69 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL38650989 | 0.68 | HPGD (0.60) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL21753196 | 0.68 | HPGD (0.79) | HPGDALDH1A1LMNAKMT2A | |
| SCHEMBL3946632 | 0.68 | HPGD (0.68) | HPGDALDH1A1L3MBTL1KMT2A | |
| SCHEMBL3121911 | 0.68 | CA1 (0.53) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL2143875 | 0.67 | NPC1 (0.50) | HDAC1HDAC6HPGDALDH1A1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |