Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120585 | 0.85 | KDM4E (0.53) | KDM4EKMT2AMMP2MGAMTDP1 | |
| SCHEMBL9282949 | 0.81 | KDM4E (0.55) | KDM4EKMT2AMMP2MGAMTDP1 | |
| Benzene SCHEMBL27872024 | 0.79 | KDM4E (0.70) | KDM4EKMT2AMMP2MGAMTDP1 | |
| SCHEMBL29350284 | 0.79 | KDM4E (0.53) | KDM4EKMT2AMMP2MGAMTDP1 | |
| SCHEMBL6080381 | 0.78 | KDM4E (0.42) | KDM4EKMT2AMMP2TDP1ALOX15 | |
| Benzene SCHEMBL27888317 | 0.77 | KDM4E (0.68) | KDM4EKMT2AMMP2MGAMTDP1 | |
| SCHEMBL1088781 | 0.77 | KDM4E (0.67) | KDM4EKMT2AMMP2MGAMTDP1 | |
| SCHEMBL30170409 | 0.77 | KDM4E (0.68) | KDM4EKMT2AMMP2MGAMTDP1 | |
| SCHEMBL29697210 | 0.77 | KDM4E (1.00) | KDM4EKMT2AMMP2MGAMTDP1 | |
| SCHEMBL171491 | 0.77 | KDM4E (1.00) | KDM4EKMT2AMMP2MGAMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010147-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2010-01-28 | — | — | WO | disclosed |